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Mass Spectrometry Facility at CQE
LCQ Fleet mass spectrometer with an ESI source (Thermo Scientific) interfaced with an HPLC-DAD (Varian).
Specifications
- Direct infusion and HPLC interface
- Mass range : 50 – 2000 Da
- Unit resolution full scan (zoom scan capable)
- Multiple fragmentation experiments, MSn (n = 10)
- pg MS and MS/MS sensitivity
Services provided
- Analysis and characterization of synthesized compounds including compounds with pharmacological applications.
- Analysis and characterization of low and medium molecular weight bioactive molecules in complex matrices.
QqTOF Impact II mass spectrometer with ESI and CaptiveSpray nanoBooster sources (Bruker) interfaced with a nanoLC (Dionex WPS-3000TPLRS).
Specifications
- Direct infusion and nanoLC interface
- Mass range: 20 – 50.000 Da
- High resolution and high mass accuracy
- MS/MS fragmentation experiments
- fmol MS and MS/MS sensitivity
Services provided
- Accurate mass measurements
- Metabolomics
- Protein identification by peptide mass fingerprint (PMF) and tandem MS
- Protein post-translational modifications using middle and top-down strategies.
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